Apoptosis in the fetal testis eliminates developmentally defective germ cell clones

DH Nguyen, B Soygur, SP Peng, S Malki, G Hu… - Nature cell …, 2020 - nature.com
… , long before oogenesis or spermatogenesis. In mouse fetal … our hypothesis that earlier errors
in germ-cell epigenetic … Apoptosis may therefore function to remove PGCs with aberrantly …

Global changes in epigenomes during mouse spermatogenesis: possible relation to germ cell apoptosis

T Koji, Y Shibata - Histochemistry and Cell Biology, 2020 - Springer
… into spermatogonia and then they enter the first wave of … be necessary for the complete
understanding of the bona fide function of the epigenomes in mammalian spermatogenesis. …

[HTML][HTML] Role of sperm apoptosis and oxidative stress in male infertility: A narrative review

A Asadi, R Ghahremani, A Abdolmaleki… - International journal of …, 2021 - ncbi.nlm.nih.gov
Apoptosis regulates the male germ cells, correct function and development from the early
In the seminiferous epithelium, spermatogenesis is accompanied by germ cell apoptosis, a …

Hormonal regulation of spermatogenesis

P Sengupta, M Arafa, H Elbardisi - … signaling in spermatogenesis …, 2019 - taylorfrancis.com
… The first wave of spermatogenesis thereby follows stem cell … testicular paracrine function
to maintain spermatogenesis, … impaired spermatogenesis, increased germ cell apoptosis and …

Ubiquitin-Proteasome System–Regulated Protein Degradation in Spermatogenesis

Y Xiong, C Yu, Q Zhang - Cells, 2022 - mdpi.com
… Although the exact function of PSMA8 in spermatogenesisgerm cell apoptosis during the
first round of spermatogenesis. … be required for spermatogenesis by regulating early wave of …

Postnatal developmental expression of apelin receptor proteins and its role in juvenile mice testis

M Das, G Gurusubramanian, VK Roy - The Journal of Steroid Biochemistry …, 2022 - Elsevier
early developmental stages and adulthood as well [35]. Germ cell apoptosis during first
wave of spermatogenesis … stage and its function remains unclear in the mouse during early

[HTML][HTML] Retinoblastoma-E2F transcription factor interplay is essential for testicular development and male fertility

JA Mäkelä, J Toppari - Frontiers in Endocrinology, 2022 - frontiersin.org
… in the cell cycle resulting in two-fold higher number of germ cells at … Subsequently, there is
a massive wave of apoptosis in pRB-… apoptosis during the first wave of spermatogenesis (43). …

Molecular regulation of copper homeostasis in the male gonad during the process of spermatogenesis

S Herman, P Lipiński, M Ogórek, R Starzyński… - International Journal of …, 2020 - mdpi.com
… that primary spermatocytes died through apoptosis [64]. In the … in primary spermatocytes is
of key importance for germ cells at … suggest that the function of ATP7B in myoid cells might be …

Characteristics of seasonal spermatogenesis in the soft-shelled turtle

H Chen, Y Huang, T Liu, A Haseeb, N Ahmed… - Animal reproduction …, 2020 - Elsevier
germ cells progress through spermatogenic stages in a temporal rather than a spatial pattern.
While apoptotic germ cells … an important function in maintaining cell shape, cell motility, …

Involvement of GLCCI1 in mouse spermatogenesis

M Takada, D Fukuhara, T Takiura… - The FASEB …, 2023 - Wiley Online Library
germ cell during spermatogenesis requires a functional … contributes to development and
maintenance during spermatogenesis.… the massive wave of germ cell apoptosis during the first